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Symbol
Name
ID
Dhfr
dihydrofolate reductase
MGI:94890
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Acute lymphoblastic leukemia
T-cell acute lymphoblastic leukemias
Lymphoma
Disease(s) Associated with DHFR
acute lymphoblastic leukemia

Mouse Phenotypes
enlarged spleen
abnormal hemopoiesis
decreased common myeloid progenitor cell number
extramedullary hematopoiesis
decreased granulocyte monocyte progenitor cell number
decreased erythroid progenitor cell number
decreased erythrocyte cell number
decreased mean corpuscular hemoglobin
increased nucleated erythrocyte cell number
Availability Mouse Genotype
Dhfrorana/Dhfrorana
Dhfrorana/Dhfr+
Dhfrtm1b(EUCOMM)Wtsi/Dhfr+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory